Ventricular Standstill Following Intravenous Erythromycin and Borderline Hypokalemia

Paroxysmal ventricular standstill.

Among the various rhythms reported in the course of a Stokes-Adams attack, one of the rarest is standstill of the ventricle as an episode during normal rhythm. Such a condition may be called paroxysmal ventricular standstill, and is to be distinguished from the condition of alternating complete block and normal rhythm to which the term paroxysmal heart block may be applied. Three cases of parox...

Paroxysmal Heart Block and Ventricular Standstill.

In auriculo-ventricular block the degree of impairment of conductivity is often found to be inconstant. Even at a time when the rhythm appears clinically to be normal, however, a cardiogram will usually show prolongation of the P-R interval. Only rarely is the conduction normal between the attacks, and the term " paroxysmal heart block " may then appropriately be applied. Reports of 18 such cas...

Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation Running title: Pezhouman et al.; Hypokalemia-induced ventricular fibrillation

Stokes-Adams attacks with simultaneous auricular and ventricular standstill.

Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation.

BACKGROUND Hypokalemia is known to promote ventricular arrhythmias, especially in combination with class III antiarrhythmic drugs like dofetilide. Here, we evaluated the underlying molecular mechanisms. METHODS AND RESULTS Arrhythmias were recorded in isolated rabbit and rat hearts or patch-clamped ventricular myocytes exposed to hypokalemia (1.0-3.5 mmol/L) in the absence or presence of dofe...